Cialis stands out among other erectile dysfunction treatment medications as it works fast (within 30 min after administration) and has a long lasting effect (around 36 hrs). This innovative drug created by Lilly ICOS LLC.Cialis (TM) pharmaceutical company was patented and sanctioned in European Union (in November 2002) and the FDA (in November 2003) as a safe and effective treatment of impotence in men. The drug comes in the form of an orally taken pill which is available in different dosages. In this article we’d like to share the most important information about this drug which will help you to understand the principle of Tadalafil (the active ingredient) action as well as educate you on basic facts about this unique ED treatment drug.
What Is Tadalafil
To understand how the Cialis active ingredient work we need to know the mechanism of the male erection. When a man is sexually stimulated the muscles in his penis start to relax allowing better blood flow to the cavernous bodies (the tube like structures responsible for genitals hardening). This relaxing is impossible without a chemical known as cyclic GMP. However, there is another substance produced in men’s bodies naturally - phosphodiesterase type 5 (PDE5). It breaks down cyclic GMP. The elder is the person, the more PDE5 he has in his system. Tadalafil inhibits PDE5 enzyme production thus giving more freedom to cyclic GMP. This is a simple explanation of the long lasting erection Cialis provides. The drug is also called "a weekend pill", since it remains in body system and performs its action for as long as 36 hours.
Administration
Cialis comes in tablets of different dosage (5, 10 and 20 mg). The appropriate dosage is appointed by the therapist after examination. The prescribed dose should not be changed or self adjusted, since the medication is rather powerful. One pill per day is enough for effective ED treatment. However, if you feel you don’t get desired effect consult your doctor about the dosage increase.
The drug is usually taken with a glass of water 30 to 60 min before sexual activity. If you suspect you have taken too much of Cialis contact the nearest poison control center or emergency room as soon as possible. Remember that the drug was prescribed especially for you, don’t share it with other people - this can damage their health.
Interactions and Contraindications
If you suffer from the following conditions, talk about these with your doctor before starting impotence treatment course:
- vision problems (especially if you have retinitis pigmentosa which is a rare inherited eye disease);
- allergic reactions (to tadalafil, foods, other medicines etc.);
- heart conditions (especially if you have a history of heart attack);
- vessel problems and stroke;
- high/low blood pressure;
- liver or kidney failure.
The drug deals with blood flow thus it is not designed right for everyone. Listen to your doctor and follow his advice, since self treating can seriously damage your health.
The drug should not be mixed with potent medications, like these:
- nitrates ( isosorbide dinitrate, nitroglycerin, amyl nitrite, isosorbide mononitrate);
- blood pressure balancing medicines;
- HIV and AIDS treatment;
- medicines assigned for prostate treatment;
- a group of drugs used for seizures (carbamazepine, phenobarbital and phenytoin);
- medications prescribed for yeast and fungal infection treatment (fluconazole, ketoconazole, voriconazole and itraconazole);
- grapefruit juice (it has been proven to postpone the action of the pills).
Side Effects
The most common side effects with this drug include: dizziness, headache, back pain, indigestion, runny nose and muscle aches. These do not require medical attention (in case they are long lasting or burdensome don’t hesitate to get your doctor's advice).
In case of more serious reactions you should report to your health care provider as soon as possible (swelling, breathing problems, priapism which is an ongoing erection lasting for more than four hours, chest pain, irregular heartbeat etc.).
There exist a lot of misconceptions regarding the drug, let's bust few of them: the pill does not enhance sexual desire, serve as a birth control or protect from sexually transmitted diseases. It is important to realize that there exist numerous causes which lead to erectile dysfunction, and Cialis does not cure the root of the problem, but effectively fights with its symptoms. It means that in case of constant sexual activity you will need to take the pill on a regular basis.